The consequences of crossing-over in the inverted region

With homologous pairing during meiosis, an inversion
loop is formed in the region of the inversion
(1). When the inverted segment is relatively
large, crossing-over may occur in this region
(2). In the daughter cells, one chromosome
may showa duplication (e. g., of segments A and
B) and a deficiency (of segment F) (3), while the
other chromosome shows deficiency of segments
A and B and duplication of segment F (4).
These chromosome segments are not balanced
(aneusomy by recombination).